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Description for Protein RAPGEF6

Rap guanine nucleotide exchange factor (GEF) 6
6 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
(PubMed Links)
Domains and Motifs:
  • CNMP: Cyclic nucleotide-monophosphate binding domain
  • RasGEFN: Guanine nucleotide exchange factor for Ras-like GTPases
  • N-terminal motif
  • PDZ: Domain present in PSD-95, Dlg, and ZO-1/2.
  • RA: Ras association (RalGDS/AF-6) domain
  • RasGEF: Guanine nucleotide exchange factor for Ras-like small GTPases
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K08020
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    PDZGEF2; RA GEF 2; Rap guanine nucleotide exchange factor; PDZ domain containing guanine nucleotide exchange factor I; PDZ domain containing guanine nucleotide exchange factor (GEF) 2; KIA001LB
    Approved Symbol:
    RAPGEF6
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 16
    Human (de-) phosphorylation sites: 16; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 11483 Entrez Gene ID: 51735 OMIM ID: 610499 Swissprot Accession: Q8TEU7; A3KN82; B7ZML2;