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Description for Protein POLR3K

polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a small essential subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor. This similarity in sequence is supported by functional studies showing that this subunit is required for proper pausing and termination during transcription. Pseudogenes of this gene are found on chromosomes 13 and 17. (PubMed Links)
Domains and Motifs:
  • ZnF_C2C2: C2C2 Zinc finger
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.7.6
    KEGG - Orthology:
    K03019
    KEGG - Pathway(s):
    hsa00230; hsa00240; hsa01100; hsa03020; hsa04623
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    C11; HsC11p; RPC11; hRPC11; EC 2.7.7.6; My010 protein; RNA plymerase III, 12.3 kd subunit; DNA-directed RNA polymerases III 12.5 kDa polypeptide; Polymerase III, RNA, subunit K
    Approved Symbol:
    POLR3K
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 16187 Entrez Gene ID: 51728 OMIM ID: 606007 Swissprot Accession: Q9Y2Y1;