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Description for Protein RAB14

RAB14, member RAS oncogene family
5 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 10/0)
(membrane: 2; microparticles: 1; platelet: 7; secretome: 1)
Summary:
RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al., 2004 [PubMed 15004230]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • RAB: Rab subfamily of small GTPases
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K07881
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Ras related protein Rab14
    Approved Symbol:
    RAB14
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 5
    Human (de-) phosphorylation sites: 5; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 06693 Entrez Gene ID: 51552 OMIM ID: 612673 Swissprot Accession: P61106;