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Description for Protein PDE7A

phosphodiesterase 7A
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
(PubMed Links)
Domains and Motifs:
  • HDc: Metal dependent phosphohydrolases with conserved 'HD' motif.
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    3.1.4.17
    KEGG - Orthology:
    K01120
    KEGG - Pathway(s):
    hsa00230
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    HCP1; TM22; PDE7; Phosphodiesterase isozyme 7; High-affinity cAMP-specific 3`,5`-cyclic phosphodiesterase 7A; EC 3.1.4.17; Phosphodiesterase 7A isoform a; Phosphodiesterase 7A isoform b
    Approved Symbol:
    PDE7A
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • 3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one(db);
  • 3-ISOBUTYL-1-METHYLXANTHINE(db);
  • Dyphylline(db);
  • Ketotifen(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01386 Entrez Gene ID: 5150 OMIM ID: 171885 Swissprot Accession: Q13946;