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Description for Protein ISYNA1

inositol-3-phosphate synthase 1
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 3)
Summary:
Myoinositol, the most common naturally occurring form of inositol, is a component of plasma membrane phospholipids and functions as a cell signaling molecule. ISYNA1 (EC 5.5.1.4), or IPS, is a rate-limiting enzyme that catalyzes the de novo synthesis of myoinositol 1-phosphate from glucose 6-phosphate (Seelan et al., 2004 [PubMed 15464731]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
5.5.1.4
KEGG - Orthology:
K01858
KEGG - Pathway(s):
hsa00562; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
ISYNA1
Approved Symbol:
ISYNA1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • 2-Deoxy-D-Glucitol 6-(E)-Vinylhomophosphonate(db);
  • 2-Deoxy-Glucitol-6-Phosphate(db);
  • Glycerol(db);
  • Nicotinamide-Adenine-Dinucleotide(db);
  • Pyrophosphate 2-(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 17163 Entrez Gene ID: 51477 OMIM ID: 611670 Swissprot Accession: Q9NPH2;