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Description for Protein LCMT1

leucine carboxyl methyltransferase 1
2 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA; MIM 176915) (De Baere et al., 1999 [PubMed 10600115]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
2.1.1.-
KEGG - Orthology:
K00599
KEGG - Pathway(s):
hsa00340; hsa00350; hsa00450
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
PPMT1; EC 2.1.1.-; Leucine carboxyl methyltransferase 1 isoform a; Leucine carboxyl methyltransferase 1 isoform b; LCMT; CGI-68; Leucine carboxyl methyltransferase; Protein-leucine O-methyltransferase
Approved Symbol:
LCMT1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 2
Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • L-Leucine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 17266 Entrez Gene ID: 51451 OMIM ID: 610286 Swissprot Accession: Q9UIC8; A6NL89;