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Description for Protein PDE3B

phosphodiesterase 3B, cGMP-inhibited
3 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
(PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
  • HDc: Metal dependent phosphohydrolases with conserved 'HD' motif.
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    3.1.4.17
    KEGG - Orthology:
    K13296
    KEGG - Pathway(s):
    hsa00230; hsa04910; hsa04914
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    cGMP inhibited 3`,5` cyclic phosphodiesterase B; CGIPDE B; CGIPDE1; CGIP1
    Approved Symbol:
    PDE3B
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 7
    Human (de-) phosphorylation sites: 7; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • (5r)-6-(4-{[2-(3-Iodobenzyl)-3-Oxocyclohex-1-En-1-Yl]Amino}Phenyl)-5-Methyl-4,5-Dihydropyridazin-3(2h)-One(db);
  • 3-ISOBUTYL-1-METHYLXANTHINE(db);
  • Hg9a-9, Nonanoyl-N-Hydroxyethylglucamide(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 5
    • Additional Identifiers:

    HPRD: 03626 Entrez Gene ID: 5140 OMIM ID: 602047 Swissprot Accession: A7E2E5; Q13370;