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Description for Protein PDE2A

phosphodiesterase 2A, cGMP-stimulated
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(undefined: 1)
Summary:
(PubMed Links)
Domains and Motifs:
  • GAF: Domain present in phytochromes and cGMP-specific phosphodiesterases.
  • SP: Signal Peptide
  • HDc: Metal dependent phosphohydrolases with conserved 'HD' motif.
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    3.1.4.17
    KEGG - Orthology:
    K01120
    KEGG - Pathway(s):
    hsa00230
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    cGSPDE; CGS-PDE; Cyclic GMP stimulated phosphodiesterase; cGMP-dependent 3`,5`-cyclic phosphodiesterase
    Approved Symbol:
    PDE2A
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 4
    Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • 3-ISOBUTYL-1-METHYLXANTHINE(db);
  • Cyclic Guanosine Monophosphate(db);
  • Tofisopam(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04041 Entrez Gene ID: 5138 OMIM ID: 602658 Swissprot Accession: O00408; Q5J793; Q8IW54;