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Description for Protein DDX47

DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene can shuttle between the nucleus and the cytoplasm, and has an RNA-independent ATPase activity. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • HELIC: helicase superfamily c-terminal domain
  • DEXDc: DEAD-like helicases superfamily
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    3.6.1.-
    KEGG - Orthology:
    K01529
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    EC 3.6.1.-; E4-DEAD box protein; Probable ATP-dependent RNA helicase DDX47; DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1; DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2; DEAD (Asp-Glu-Ala-Asp) box polypeptide 47; E4-DBP; DEAD box polypeptide 47
    Approved Symbol:
    DDX47
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 7
    Human (de-) phosphorylation sites: 7; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 10863 Entrez Gene ID: 51202 OMIM ID: - Swissprot Accession: Q9H0S4; Q9UI98;