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Description for Protein HSD17B12

hydroxysteroid (17-beta) dehydrogenase 12
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 3/0)
(membrane: 2; platelet: 2)
Summary:
The enzyme 17-beta hydroxysteroid dehydrogenase-12 (HSD17B12) uses NADPH to reduce 3-ketoacyl-CoA to 3-hydroxyacyl-CoA during the second step of fatty acid elongation.[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    1.1.1.-; 1.1.1.62
    KEGG - Orthology:
    K00044
    K10251
    KEGG - Pathway(s):
    hsa00140; hsa01040; hsa01100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    KAR; Hydroxysteroid 17 beta dehydrogenase 12
    Approved Symbol:
    HSD17B12
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 3
    • Additional Identifiers:

    HPRD: 09989 Entrez Gene ID: 51144 OMIM ID: 609574 Swissprot Accession: Q53GQ0;