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Description for Protein CLEC4A

C-type lectin domain family 4, member A
1 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • LECTIN_C: C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K10057
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    C type lectin superfamily 6; Lectin like immunoreceptor; Dendritic cell immunoreceptor; LLIR; DCIR; DDB27; Lectin C type superfamily member 6; CLECSF6; C type lectin DDB27; HDCGC13P; C type lectin superfamily member 6 isoform 1; C type lectin superfamily member 6 isoform 2; C type lectin superfamily member 6 isoform 3; C type lectin superfamily member 6 isoform 4
    Approved Symbol:
    CLEC4A
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 4 : 1
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 05604 Entrez Gene ID: 50856 OMIM ID: 605306 Swissprot Accession: Q9UMR7;