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Description for Protein NKX3-1

NK3 homeobox 1
5 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • HOX: Homeodomain

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K09348
    KEGG - Pathway(s):
    hsa05200; hsa05215
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Homeo box 3A, NK; NK Homeobox, family 3, member A; Homeobox protein Nkx 3.1
    Approved Symbol:
    NKX3-1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 6
    Human (de-) phosphorylation sites: 6; No platelet phosphorylation sites

    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available


    Associated Genetic Diseases:

    None Available
    Predicted Transmembrane Domains:
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 03620 Entrez Gene ID: 4824 OMIM ID: 602041 Swissprot Accession: Q99801