Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein NHP2L1

NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
8 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It binds to the 5' stem-loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K12845
KEGG - Pathway(s):
hsa03040
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
OTK27; NHPX; NHP2 non-histone chromosome protein 2-like 1; [U4/U6.U5] tri-snRNP 15.5 kD RNA binding protein; High mobility group-like nuclear protein 2 homolog 1; SNU13
Approved Symbol:
NHP2L1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 3
Human (de-) phosphorylation sites: 3; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • Alpha-Hydroxy-Beta-Phenyl-Propionic Acid(db);
  • ANISOMYCIN(db);
  • N-{[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide(db);
  • PUROMYCIN(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03197 Entrez Gene ID: 4809 OMIM ID: 601304 Swissprot Accession: P55769; Q6FHM6; C9J9R8;