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Description for Protein NFYC

nuclear transcription factor Y, gamma
23 total interacting proteins; 5 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available

Gene Ontology:
Gene Ontology Annotations

KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K08066
KEGG - Pathway(s):
hsa04612
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
HSM; CCAAT binding factor subunit C; HAP5; NF-YC; H1TF2A; Transactivator HSM-1; CCAAT transcription binding factor subunit gamma; Histone H1 transcription factor large subunit 2A; Transactivator HSM-1/2; Nuclear transcription factor Y subunit C; Transcription factor NF-Y, C subunit; CCAAT binding factor, C subunit; CBFCb
Approved Symbol:
NFYC
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites

Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available


Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 6 : 0
  • Isoform 5 : 0
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 05633 Entrez Gene ID: 4802 OMIM ID: 605344 Swissprot Accession: Q5T6K9Q13952Q59GY4