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Description for Protein NEDD4

neural precursor cell expressed, developmentally down-regulated 4
61 total interacting proteins; 26 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
(PubMed Links)
Domains and Motifs:
  • WW: Domain with 2 conserved Trp (W) residues
  • C2: Protein kinase C conserved region 2 (CalB)
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    6.3.2.19
    KEGG - Orthology:
    K10591
    KEGG - Pathway(s):
    hsa04120; hsa04144
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Neural precursor cell expressed, developmentally down-regulated 4 isoform 1; Neural precursor cell expressed, developmentally down-regulated 4 isoform 2; Neural precursor cell expressed, developmentally down-regulated 4; Ubiquitin protein ligase Nedd 4; E3 ubiquitin-protein ligase Nedd-4; KIAA0093
    Approved Symbol:
    NEDD4
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 14
    Human (de-) phosphorylation sites: 14; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03786 Entrez Gene ID: 4734 OMIM ID: 602278 Swissprot Accession: P46934;