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Description for Protein NDUFV3

NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 1)
Summary:
The protein encoded by this gene is one of at least forty-one subunits that make up the NADH-ubiquinone oxidoreductase complex. This complex is part of the mitochondrial respiratory chain and serves to catalyze the rotenone-sensitive oxidation of NADH and the reduction of ubiquinone. The encoded protein is one of three proteins found in the flavoprotein fraction of the complex. The specific function of the encoded protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
1.6.5.3; 1.6.99.3
KEGG - Orthology:
K03944
KEGG - Pathway(s):
hsa00190; hsa01100; hsa05010; hsa05012; hsa05016
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
CI-9KD; NADH-ubiquinone oxidoreductase flavoprotein 3, 10kD; NADH dehydrogenase (ubiquinone) flavoprotein 3 (10kD); NADH-ubiquinone oxidoreductase 9 kD subunit; Complex I, mitochondrial respiratory chain, 10-kD subunit; EC 1.6.99.3; Complex I-9KD; NADH-ubiquinone oxidoreductase 9 kDa subunit, mitochondrial; NADH-ubiquinone oxidoreductase flavoprotein 3 isoform a; NADH-ubiquinone oxidoreductase flavoprotein 3 isoform b; EC 1.6.5.3
Approved Symbol:
NDUFV3
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 16
Human (de-) phosphorylation sites: 16; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • NADH(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03716 Entrez Gene ID: 4731 OMIM ID: 602184 Swissprot Accession: P56181;