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Description for Protein NDUFB2

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 2/0)
(membrane: 1; platelet: 7)
Summary:
The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays a important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Hydropathy analysis revealed that this subunit and 4 other subunits have an overall hydrophilic pattern, even though they are found within the hydrophobic protein (HP) fraction of complex I. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
1.6.5.3; 1.6.99.3
KEGG - Orthology:
K03958
KEGG - Pathway(s):
hsa00190; hsa01100; hsa05010; hsa05012; hsa05016
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
AGGG; CI-AGGG; EC 1.6.5.3; EC 1.6.99.3; Complex I-AGGG; NADH-ubiquinone oxidoreductase AGGG subunit; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
Approved Symbol:
NDUFB2
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • NADH(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 11953 Entrez Gene ID: 4708 OMIM ID: 603838 Swissprot Accession: O95178; C9JUH1; A4D1T5;