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Description for Protein MYOD1

myogenic differentiation 1
68 total interacting proteins; 25 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • BASIC: Basic domain in HLH proteins of MYOD family
  • NLS: Nuclear localization signal
  • HLH: helix loop helix domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K09064
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Myogenic factor 3; MYF3; Myoblast determination protein 1; Myogenic factor MYF-3; MyoD
    Approved Symbol:
    MYOD1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01166 Entrez Gene ID: 4654 OMIM ID: 159970 Swissprot Accession: P15172;