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Description for Protein MYL6

myosin, light chain 6, alkali, smooth muscle and non-muscle
7 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(platelet: 2)
Summary:
Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • EF: EF-hand, calcium binding motif

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K12751
    KEGG - Pathway(s):
    hsa04270
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Smooth muscle and non-muscle myosin alkali light chain isoform 1; Smooth muscle and non-muscle myosin alkali light chain isoform 2; Myosin, light polypeptide 6 alkali, smooth muscle and non-muscle; ESMLC; LC17A; LC17B; MLC1SM; MLC3NM; MLC3SM; LC17-GI; LC17-NM; Myosin light chain alkali 3
    Approved Symbol:
    MYL6
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 12
    Human (de-) phosphorylation sites: 12; No platelet phosphorylation sites

    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available


    Associated Genetic Diseases:

    None Available
    Predicted Transmembrane Domains:
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 17618 Entrez Gene ID: 4637 OMIM ID: 609931 Swissprot Accession: P60660