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Description for Protein ASNS

asparagine synthetase (glutamine-hydrolyzing)
4 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
6.3.5.4
KEGG - Orthology:
K01953
KEGG - Pathway(s):
hsa00250; hsa00910; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
Human complement for sensitive mutant ts11; Glutamine dependent asparagine synthetase; TS11 cell cycle control protein; AS; TS11; EC 6.3.5.4
Approved Symbol:
ASNS
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 2
Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • Adenosine triphosphate(db);
  • L-Asparagine(db);
  • L-Aspartic Acid(db);
  • L-Glutamic Acid(db);
  • L-Glutamine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00153 Entrez Gene ID: 440 OMIM ID: 108370 Swissprot Accession: P08243;