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Description for Protein CD200

CD200 molecule
2 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • Ig_LIKE: Immunoglobulin like
  • TM: Transmembrane domain
  • IG: Immunoglobulin
  • SP: Signal Peptide
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K06556
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    CD200 antigen isoform b; CD200 antigen isoform a precursor; OX2; Membrane glycoprotein MRC OX-2; My033 protein; OX-2 membrane glycoprotein; MOX1; MOX2; MRC; OX-2; Antigen identified by monoclonal antibody MRC OX-2; CD200 antigen; MRC OX-2 antigen
    Approved Symbol:
    CD200
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 2
  • Isoform 2 : 0
  • Isoform 1 : 2
    • Additional Identifiers:

    HPRD: 01124 Entrez Gene ID: 4345 OMIM ID: 155970 Swissprot Accession: P41217;