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Description for Protein MOS

v-mos Moloney murine sarcoma viral oncogene homolog
3 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
MOS is a serine/threonine kinase that activates the MAP kinase cascade through direct phosphorylation of the MAP kinase activator MEK (MAP2K1; MIM 176872) (Prasad et al., 2008 [PubMed 18246541]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • S_T_Y_Kinase: Protein kinase
  • unclassified specificity
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.11.1
    KEGG - Orthology:
    K04367
    KEGG - Pathway(s):
    hsa04010; hsa04114; hsa04810; hsa04914
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    MSV; Oncogene mos; Proto oncogene serine/threonine protein kinase mos; Oocyte maturation factor mos; MGC119962; MGC119963; EC 2.7.11.1
    Approved Symbol:
    MOS
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 1
    Human phosphorylation targets: 1; Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01816 Entrez Gene ID: 4342 OMIM ID: 190060 Swissprot Accession: P00540;