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Description for Protein MNAT1

menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)
19 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Cyclin-dependent kinases (CDKs), which play an essential role in cell cycle control of eukaryotic cells, are phosphorylated and thus activated by the CDK-activating kinase (CAK). CAK is a multisubunit protein that includes CDK7 (MIM 601955), cyclin H (CCNH; MIM 601953), and MAT1. MAT1 (for 'menage a trois-1') is involved in the assembly of the CAK complex.[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • RING: Ring finger

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K10842
    KEGG - Pathway(s):
    hsa03420
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    CAP35; Menage a trois; Menage a trois 1; RING finger protein MAT1; Cyclin G1 interacting protein; CDK7/cyclin H assembly factor; CDK-activating kinase assembly factor MAT1
    Approved Symbol:
    MNAT1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 4
    Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites

    Phosphorylation Targets:
    Total phosphorylation targets: 1
    Human phosphorylation targets: 1; Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available


    Associated Genetic Diseases:

    None Available
    Predicted Transmembrane Domains:
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 04042 Entrez Gene ID: 4331 OMIM ID: 602659 Swissprot Accession: P51948