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Description for Protein MGAT3

mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. The enzyme encoded by this gene transfers a GlcNAc residue to the beta-linked mannose of the trimannosyl core of N-linked oligosaccharides and produces a bisecting GlcNAc. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
  • SP: Signal Peptide
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.4.1.144
    KEGG - Orthology:
    K00737
    KEGG - Pathway(s):
    hsa00510; hsa01100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase; GNT3; GNT-III; UDP-N-acetylglucosamine:beta-D-mannoside beta-1,4-N-acetylglucosaminyltransfrease; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III; GlcNAc-T III; GGNT3
    Approved Symbol:
    MGAT3
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 1
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 07058 Entrez Gene ID: 4248 OMIM ID: 604621 Swissprot Accession: Q09327;