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Description for Protein METTL1

methyltransferase like 1
4 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
2.1.1.33
KEGG - Orthology:
K03439
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
tRNA(m7G46) methyltransferase; C12orf1; TRM8; YDL201w; Methyltransferase-like protein 1; D1075-like gene product; tRNA (guanine-N(7)-)-methyltransferase; EC 2.1.1.33; Methyltransferase-like protein 1 isoform a; Methyltransferase-like protein 1 isoform c
Approved Symbol:
METTL1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 1
Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 06834 Entrez Gene ID: 4234 OMIM ID: 604466 Swissprot Accession: Q53FS9; Q9UBP6;