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Description for Protein MCM5

minichromosome maintenance complex component 5
23 total interacting proteins; 6 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • MCM: minichromosome maintenance proteins
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K02209
    KEGG - Pathway(s):
    hsa03030; hsa04110
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Cell division cycle 46; P1-CDC46; DNA replication licensing factor MCM5; CDC 46; MCM5 minichromosome maintenance deficient 5, cell division cycle 46; MGC5315; Minichromosome maintenance deficient protein 5
    Approved Symbol:
    MCM5
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 3
    Human (de-) phosphorylation sites: 3; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04075 Entrez Gene ID: 4174 OMIM ID: 602696 Swissprot Accession: P33992; B1AHB0;