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Description for Protein MAP2

microtubule-associated protein 2
18 total interacting proteins; 12 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(secretome: 1)
Summary:
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K10430
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
Microtubule associated protein 2 isoform 4; Microtubule associated protein 2 isoform 1; Microtubule associated protein 2 isoform 2; MAP2A; MAP2B; MAP2C; DKFZp686I2148; Microtubule-associated protein 2 isoform 5
Approved Symbol:
MAP2
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 103
Human (de-) phosphorylation sites: 103; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • Estramustine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 5 : 0
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01140 Entrez Gene ID: 4133 OMIM ID: 157130 Swissprot Accession: P11137; Q8IUX2; Q6NYC5;