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Description for Protein MAP1B

microtubule-associated protein 1B
33 total interacting proteins; 15 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(phosphoproteome: 1; undefined: 1)
Summary:
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important role in development and function of the nervous system. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K10429
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Microtubule associated protein 1B isoform 2; Microtubule associated protein 1B isoform 1; MAP1 light chain LC1; MAP5; FUTSCH; DKFZp686F1345
    Approved Symbol:
    MAP1B
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 351
    Human (de-) phosphorylation sites: 351; Platelet phosphorylation sites: 2
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01139 Entrez Gene ID: 4131 OMIM ID: 157129 Swissprot Accession: P46821; Q6PJD3; Q86X89;