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Description for Protein MAG

myelin associated glycoprotein
17 total interacting proteins; 6 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • Ig_LIKE: Immunoglobulin like
  • IGC2: Immunoglobulin C-2 Type
  • TM: Transmembrane domain

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K06771
    KEGG - Pathway(s):
    hsa04514
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Myelin associated glycoprotein isoform b precursor; Myelin associated glycoprotein isoform a precursor; Sialic acid binding immunoglobulin like lectin 4A; Myelin associated glycoprotein; GMA; S-MAG
    Approved Symbol:
    MAG
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 4
    Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites

    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available


    Associated Genetic Diseases:

    None Available
    Predicted Transmembrane Domains:
  • Isoform 2 : 1
  • Isoform 1 : 1
  • Additional Identifiers:

    HPRD: 01160 Entrez Gene ID: 4099 OMIM ID: 159460 Swissprot Accession: Q567S4P20916Q15489