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Description for Protein SMAD9

SMAD family member 9
111 total interacting proteins; 49 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 3)
Summary:
The protein encoded by this gene is a member of the SMAD family, which transduces signals from TGF-beta family members. The encoded protein is activated by bone morphogenetic proteins and interacts with SMAD4. Two transcript variants encoding different isoforms have been found for this gene. (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K04676
    KEGG - Pathway(s):
    hsa04350
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    MAD mothers against decapentaplegic homolog 9; SMA and MAD related protein 9; Mother against dpp (Mad) related protein; Mothers against DPP homolog 9; MADH6; SMAD8A; SMAD8B; MADH9
    Approved Symbol:
    SMAD9
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 6
    Human (de-) phosphorylation sites: 6; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04484 Entrez Gene ID: 4093 OMIM ID: 603295 Swissprot Accession: O15198; Q5TBA1;