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Description for Protein MIR17HG

MIR17 host gene (non-protein coding)
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
MicroRNAs (miRNAs) are small regulatory RNAs that control gene expression by binding to complementary sites within target mRNAs and mediating their degradation or translational repression. MIR17HG is the host gene for the MIR17-92 cluster, which is also called ONCOMIR1, and encodes a polycistronic primary transcript that yields at least 6 mature miRNAs: MIR17 (MIM 609416), MIR18 (MIR18A; MIM 609417), MIR19A (MIR19A1; MIM 609418), MIR19B (MIR19B1; MIM 609419), MIR20 (MIR20A; MIM 609420), and MIR92 (MIR92A1; MIM 609422). MIR17-92 functions in cell survival, proliferation, differentiation, and angiogenesis and is the primary target of genomic amplification of chromosome 13q31 that occurs in several lymphomas and solid tumors (summary by Olive et al., 2009 [PubMed 20008935]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
None Available

Gene Ontology:
Gene Ontology Annotations

KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
None Available
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
-
Approved Symbol:
MIR17HG
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites

Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available


Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 1
  • Additional Identifiers:

    HPRD: 12617 Entrez Gene ID: 407975 OMIM ID: 609415 Swissprot Accession: -