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Description for Protein LTA4H

leukotriene A4 hydrolase
6 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 2/0)
(microparticles: 1; secretome: 1)
Summary:
(PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
3.3.2.6
KEGG - Orthology:
K01254
KEGG - Pathway(s):
hsa00590; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
-
Approved Symbol:
LTA4H
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 5
Human (de-) phosphorylation sites: 5; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • (2S)-2-amino-5-oxo-5-[(4-phenylmethoxyphenyl)amino]pentanoic acid(db);
  • (4-fluorophenyl)(pyridin-4-yl)methanone(db);
  • (R)-pyridin-4-yl[4-(2-pyrrolidin-1-ylethoxy)phenyl]methanol(db);
  • 1-(2,2'-bithiophen-5-yl)methanamine(db);
  • 1-(4-thiophen-2-ylphenyl)methanamine(db);
  • 3-(Benzyloxy)Pyridin-2-Amine(db);
  • 4-(2-amino-1,3-thiazol-4-yl)phenol(db);
  • 4-amino-N-[4-(benzyloxy)phenyl]butanamide(db);
  • 5-[2-(1H-pyrrol-1-yl)ethoxy]-1H-indole(db);
  • 5-[2-(4-hydroxyphenyl)ethyl]benzene-1,3-diol(db);
  • Acetate Ion(db);
  • Bestatin(db);
  • Imidazole(db);
  • N-(pyridin-3-ylmethyl)aniline(db);
  • N-benzyl-4-[(2R)-pyrrolidin-2-ylmethoxy]aniline(db);
  • N-methyl-1-(2-thiophen-2-ylphenyl)methanamine(db);
  • N-[(2R)-2-benzyl-4-(hydroxyamino)-4-oxobutanoyl]-L-alanine(db);
  • N-[3-[(1-Aminoethyl)(Hydroxy)Phosphoryl]-2-(1,1'-Biphenyl-4-Ylmethyl)Propanoyl]Alanine(db);
  • N-[4-(benzyloxy)phenyl]glycinamide(db);
  • {4-[(2R)-pyrrolidin-2-ylmethoxy]phenyl}(4-thiophen-3-ylphenyl)methanone(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01056 Entrez Gene ID: 4048 OMIM ID: 151570 Swissprot Accession: P09960;