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Description for Protein LSP1

lymphocyte-specific protein 1
3 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
None Available
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
F-actin binding and cytoskeleton associated protein; Leufactin; Lymphocyte-specific antigen WP34; Lymphocyte-specific protein pp52; Lymphocyte-specific protein 1 isoform 2; Lymphocyte-specific protein 1 isoform 1; Leukocyte-specific protein 1; Lymphocyte specific protein 1; pp52; Protein pp52; 52 kDa phosphoprotein; Lymphocyte specific antigen WP34; 47 kDa actin binding protein; WP34
Approved Symbol:
LSP1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 21
Human (de-) phosphorylation sites: 21; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01083 Entrez Gene ID: 4046 OMIM ID: 153432 Swissprot Accession: P33241; B3KPP1;