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Description for Protein LGALS9

lectin, galactoside-binding, soluble, 9
3 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • GLECT: Galectin
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K10093
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Lectin galactoside binding soluble 9; Ecalectin; HOM-HD-21; MGC117375; MGC125973; MGC125974; Galectin 9 short isoform; Galectin 9 long isoform
    Approved Symbol:
    LGALS9
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • (R)-1-Para-Nitro-Phenyl-2-Azido-Ethanol(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03528 Entrez Gene ID: 3965 OMIM ID: 601879 Swissprot Accession: O00182; Q3B8N1; A7VJG6;