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Description for Protein ACAT2

acetyl-CoA acetyltransferase 2
3 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 3/0)
(membrane: 1; platelet: 1; secretome: 1)
Summary:
The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available

Gene Ontology:
Gene Ontology Annotations

KEGG - Enzyme ID(s):
2.3.1.9
KEGG - Orthology:
K00626
KEGG - Pathway(s):
hsa00071; hsa00072; hsa00280; hsa00310; hsa00380; hsa00620; hsa00640; hsa00650; hsa00900; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
Acetocoenzyme A acetyltransferase 2; Acetoacetyl-CoA thiolase; EC 2.3.1.9
Approved Symbol:
ACAT2
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites

Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • Coenzyme A(db);
  • S-Hydroxycysteine(db)


    Associated Genetic Diseases:

    None Available
  • Predicted Transmembrane Domains:
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 00006 Entrez Gene ID: 39 OMIM ID: 100678 Swissprot Accession: Q9BWD1