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Description for Protein KRT9

keratin 9
2 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 4/0)
(alpha granules: 1; membrane: 1; platelet: 1; secretome: 1)
Summary:
This gene encodes the type I keratin 9, an intermediate filament chain expressed only in the terminally differentiated epidermis of palms and soles. Mutations in this gene cause epidermolytic palmoplantar keratoderma. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K07604
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Cytokeratin 9; CK 9; Keratin, type I cytoskeletal 9
    Approved Symbol:
    KRT9
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 6
    Human (de-) phosphorylation sites: 6; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

  • Palmoplantar keratoderma, epidermolytic(Pd);
  • Palmoplantar keratoderma, epidermolytic, with knuckle pads(Pd)
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 06351 Entrez Gene ID: 3857 OMIM ID: 607606 Swissprot Accession: P35527;