Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein ARF6

ADP-ribosylation factor 6
35 total interacting proteins; 23 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 2/1)
(platelet: 2; undefined: 1)
Summary:
This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • ARF: ARF-like small GTPases
  • ARF, ADP-ribosylation factor
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K07941
    KEGG - Pathway(s):
    hsa04144; hsa04666
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    DKFZp564M0264
    Approved Symbol:
    ARF6
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • 5'-Guanosine-Diphosphate-Monothiophosphate(db);
  • Guanosine-5'-Diphosphate(db);
  • MYRISTIC ACID(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02714 Entrez Gene ID: 382 OMIM ID: 600464 Swissprot Accession: P62330; Q6FGZ2;