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Description for Protein KIF5A

kinesin family member 5A
14 total interacting proteins; 6 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 2/0)
(platelet: 2)
Summary:
This gene encodes a member of the kinesin family of proteins. Members of this family are part of a multisubunit complex that functions as a microtubule motor in intracellular organelle transport. Mutations in this gene cause autosomal dominant spastic paraplegia 10. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • KISC: Kinesin motor, catalytic domain. ATPase.
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K10396
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    NKHC; Neuronal kinesin heavy chain; Kinesin heavy chain isoform 5A; Kinesin heavy chain neuron specific 1; NKHC1; Spastic paraplegia 10 (autosomal dominant)
    Approved Symbol:
    KIF5A
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

  • Spastic paraplegia 10(Pd)
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 09108 Entrez Gene ID: 3798 OMIM ID: 602821 Swissprot Accession: Q12840;