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Description for Protein KCNS3

potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • BTB: Broad-Complex, Tramtrack and Bric a brac
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K04933
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Potassium voltage gated channel, delayed-rectifier, subfamily S, member 3; Voltage gated channel 9.3; Potassium voltage gated channel subfamily S member 3; Potassium channel Kv9.3; Delayed rectifier K+ channel alpha subunit 3; Shab-related delayed rectifier K+ channel alpha subunit 3
    Approved Symbol:
    KCNS3
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 3
    • Additional Identifiers:

    HPRD: 04865 Entrez Gene ID: 3790 OMIM ID: 603888 Swissprot Accession: Q9BQ31; Q4ZFY1;