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Description for Protein KCNK1

potassium channel, subfamily K, member 1
3 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K04912
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Potassium channel KCNO1; TWIK1; Potassium channel, weakly inward rectifying with twin P domains 1; HOHO1; KCNO1; DPK; HOHO; Inward rectifying potassium channel protein TWIK 1
    Approved Symbol:
    KCNK1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Ibutilide(db);
  • Quinidine(db);
  • Quinidine barbiturate(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 5
    • Additional Identifiers:

    HPRD: 03447 Entrez Gene ID: 3775 OMIM ID: 601745 Swissprot Accession: O00180;