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Description for Protein AGRN

agrin
3 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Agrin is a neuronal aggregating factor that induces the aggregation of acetylcholine receptors and other postsynaptic proteins on muscle fibers and is crucial for the formation of the neuromuscular junction.[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • SEA: Domain found in sea urchin sperm protein, enterokinase, agrin
  • EGFCA: Calcium-binding EGF-like domain
  • LAMG: Laminin G domain
  • EGF: Epidermal growth factor-like domain.
  • FOLN: Follistatin-N-terminal domain-like
  • KAZAL: Kazal type serine protease inhibitors
  • EGFLAM: Laminin-type epidermal growth factor-like domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K06254
    KEGG - Pathway(s):
    hsa04512
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    FLJ45064
    Approved Symbol:
    AGRN
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 10550 Entrez Gene ID: 375790 OMIM ID: 103320 Swissprot Accession: O00468; Q5XG79;