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Description for Protein KCNF1

potassium voltage-gated channel, subfamily F, member 1
4 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily F. This gene is intronless and expressed in all tissues tested, including the heart, skeletal muscle, brain, kidney, and pancreas. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • TM: Transmembrane domain
  • BTB: Broad-Complex, Tramtrack and Bric a brac

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K04899
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Kv5.1; KCNF; Potassium channel KH1; Potassium channel Kv5.1; Potassium voltage-gated channel, subfamily F; Potassium voltage-gated channel subfamily F member 1
    Approved Symbol:
    KCNF1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites

    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available


    Associated Genetic Diseases:

    None Available
    Predicted Transmembrane Domains:
  • Isoform 1 : 4
  • Additional Identifiers:

    HPRD: 04808 Entrez Gene ID: 3754 OMIM ID: 603787 Swissprot Accession: Q9H3M0Q585L3