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Description for Protein GSTK1

glutathione S-transferase kappa 1
26 total interacting proteins; 16 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 7/1)
(alpha granules: 1; membrane: 3; platelet: 9; secretome: 1)
Summary:
This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants. (PubMed Links)
Domains and Motifs:
None Available

Gene Ontology:
Gene Ontology Annotations

KEGG - Enzyme ID(s):
2.5.1.18
KEGG - Orthology:
K13299
KEGG - Pathway(s):
hsa00480; hsa00980; hsa00982; hsa04146
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
hGSTK1; GSTK1-1; GST 13-13; EC 2.5.1.18; GST class kappa; Glutathione S-transferase subunit 13; Glutathione S transferase subunit 13 homolog
Approved Symbol:
GSTK1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 4
Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites

Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • Glutathione(db);
  • GLUTATHIONE SULFINATE(db)


    Associated Genetic Diseases:

    None Available
  • Predicted Transmembrane Domains:
  • Isoform 5 : 0
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 13613 Entrez Gene ID: 373156 OMIM ID: 602321 Swissprot Accession: Q6FII1Q9Y2Q3Q6P4H0