Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein JUN

jun proto-oncogene
160 total interacting proteins; 56 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • BRLZ: basic region leucin zipper
  • NLS: Nuclear localization signal
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K04448
    KEGG - Pathway(s):
    hsa04010; hsa04012; hsa04310; hsa04510; hsa04620; hsa04660; hsa04662; hsa04722; hsa04912; hsa05120; hsa05140; hsa05142; hsa05200; hsa05210; hsa05211
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Protooncogene c jun; Jun
    Approved Symbol:
    JUN
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 12
    Human (de-) phosphorylation sites: 12; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Arsenic trioxide(db);
  • Irbesartan(db);
  • Vinblastine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01302 Entrez Gene ID: 3725 OMIM ID: 165160 Swissprot Accession: P05412;