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Description for Protein IRF7

interferon regulatory factor 7
17 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • IRF: interferon regulatory factor
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K09447
    KEGG - Pathway(s):
    hsa04620; hsa04622; hsa04623
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    IRF7A; IRF-7H; Interferon regulatory factor 7 isoform b; Interferon regulatory factor-7H; IRF7B; IRF7C; Interferon regulatory factor 7 isoform d; Interferon regulatory factor 7 isoform a
    Approved Symbol:
    IRF7
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 18
    Human (de-) phosphorylation sites: 18; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 05441 Entrez Gene ID: 3665 OMIM ID: 605047 Swissprot Accession: Q92985;