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Description for Protein INPP5A

inositol polyphosphate-5-phosphatase, 40kDa
2 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(membrane: 1)
Summary:
The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
3.1.3.56
KEGG - Orthology:
K01106
KEGG - Pathway(s):
hsa00562; hsa01100; hsa04070
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
Inositol polyphosphate 5 phosphatase, 40 KD; Type 1 inositol 1,4,5 trisphosphate 5 phosphatase; 5PTASE; MGC116947; MGC116949; DKFZp434A1721; InsP3 5-phosphatase; CTCL tumor antigen HD-CL-02; 43 kDa inositol polyphosphate 5-phophatase; Inositol trisphosphate-5-phosphatase, 40kD; Type I inositol-1,4,5-trisphosphate 5-phophatase; 3.1.3.56
Approved Symbol:
INPP5A
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 1
Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02521 Entrez Gene ID: 3632 OMIM ID: 600106 Swissprot Accession: Q14642; Q8N6C1;