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Description for Protein CXCL10

chemokine (C-X-C motif) ligand 10
9 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • SCY: Intercrine alpha family (small cytokine C-X-C) (chemokine CXC).
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K12671
    KEGG - Pathway(s):
    hsa04060; hsa04062; hsa04620; hsa04622; hsa04623
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Chemokine, CXC motif, ligand 10; Small inducible cytokine subfamily B, member 10; Interferon-gamma- induced factor; MOB1; SCYB10; INP10; Interferon gamma-induced precursor; Gamma-IP10; IP-10
    Approved Symbol:
    CXCL10
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • N-Methylleucine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 00930 Entrez Gene ID: 3627 OMIM ID: 147310 Swissprot Accession: P02778;