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Description for Protein TICAM2

toll-like receptor adaptor molecule 2
15 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
TIRP is a Toll/interleukin-1 receptor (IL1R; MIM 147810) (TIR) domain-containing adaptor protein involved in Toll receptor signaling (see TLR4; MIM 603030).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • TIR: Toll - interleukin 1 - resistance
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K05409
    KEGG - Pathway(s):
    hsa04620
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    TRAM; TIRP; TIRAP3; TIRAP3a short form; TRIF related adaptor molecule; TIR containing adapter molecule 2; Toll interleukin1 receptor domain containing protein
    Approved Symbol:
    TICAM2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 16313 Entrez Gene ID: 353376 OMIM ID: 608321 Swissprot Accession: Q86XR7;