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Description for Protein ACADS

acyl-CoA dehydrogenase, C-2 to C-3 short chain
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 3/0)
(platelet: 3; secretome: 1)
Summary:
This gene encodes a a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with Short Chain Acyl-CoA Dehydrogenase Deficiency. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
1.3.99.2
KEGG - Orthology:
K00248
KEGG - Pathway(s):
hsa00071; hsa00280; hsa00650; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
Acyl CoA dehydrogenase; SCAD; Acyl CoA dehydrogenase, C 2 to C 3 short chain
Approved Symbol:
ACADS
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • Acetoacetyl-Coenzyme A(db);
  • Flavin-Adenine Dinucleotide(db);
  • NADH(db)

    Associated Genetic Diseases:

  • SCAD deficiency(Pd)
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 06053 Entrez Gene ID: 35 OMIM ID: 606885 Swissprot Accession: P16219;