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Description for Protein HSPA9

heat shock 70kDa protein 9 (mortalin)
14 total interacting proteins; 5 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 7/0)
(ATP binding: 1; microparticles: 1; platelet: 6; secretome: 1)
Summary:
This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2. (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K04043
KEGG - Pathway(s):
hsa03018
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
MOT2; MOT; PBP74; GRP75; HSPA9; p66 mortalin; Mortalin, perinuclear; Peptide binding protein 74; Heat shock 70 KD protein 9; Heat shock 70 KD protein 9B; Stress 70 protein, mitochondrial
Approved Symbol:
HSPA9
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 20
Human (de-) phosphorylation sites: 20; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02770 Entrez Gene ID: 3313 OMIM ID: 600548 Swissprot Accession: P38646;